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زیست شناسی::
کلاهک اپیدرمی رأسی
An outer epidermal thickening called the apical epidermal cap (ABC; green) covers the wound.
These progenitor cells form a mass of proliferative cells directly beneath the AEC that constitutes the blastema (red).
Formation of the apical epidermal cap and regeneration blastema
the wound epidermis thickens to form the apical epidermal cap (AEC) (see Figure 22.17B), which acts similarly to the apical ectodermal ridge during normal limb development (see Chapter 19; Han et al. 2001).
Thus, the previously well-structured limb region at the cut edge of the stump forms a proliferating mass of indistinguishable cells just beneath the apical epidermal cap.
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